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Ideal for work requiring high throughput
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Mount vessel/ring preparations between 30um and 3mm
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Direct data streaming to MyoDAQ Acquisition
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Reliable, flexible & trusted
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The 320A Single Wire Myograph System is specifically designed for high-precision studies of small vessels ranging from 30 μm to 3 mm in diameter. It enables detailed analysis of vascular function by mounting the vessel as a ring preparation on two parallel stainless-steel wires. These wires are secured to two mounting jaws—one connected to a precision micrometer for manual control of vessel circumference and stretch, and the other to a high-sensitivity force transducer for accurate measurement of isometric tension.
The vessel is housed in a 10 mL acid-resistant stainless-steel chamber, which is temperature-controlled and can be sealed with a lid featuring ports for rapid suction, refilling, and oxygenation. A built-in optical window at the chamber base allows for real-time morphological observation or fluorescence imaging using an inverted microscope. During experiments, the vessel is maintained in a physiological salt solution at 37°C, continuously bubbled with oxygen to ensure viability for up to 12 hours. After mounting and equilibration, the system facilitates determination of the passive length–tension relationship, with the vessel circumference held constant throughout the experiment. Test compounds can be added directly to the chamber, enabling precise assessment of contractility and pharmacological reactivity under isometric conditions. An optional electronic valve can be integrated for automated chamber drainage and fluid control, enhancing workflow efficiency. The system is operated via the intuitive Wire Interface touchscreen, making setup and operation straightforward. Data acquisition is handled by MyoDAQ software, which supports multi-channel recording and flexible data selection throughout the experiment. Results can be exported as full datasets or selected traces for advanced analysis or external visualization. |
Related Products
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Wire Myograph Chamber# Ring-mounted segments - 30µm to 3mm # Fine scale micrometer for accurate tension control # Force range ±200mN # Acid resistent stainless steel chamber # Optical base window for imaging |
Interface Unit
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