Muscle Strip System - 840MD4-Channel high throughput MyoDYNAMIC Muscle Strip System with the capacity to perform isometric, eccentric, and concentric muscle contraction studies under a range of conditions.
|
|
Can be fully controlled by PC software
|
Perform eccentric & concentric contraction studies
|
Integrated gassing, heating & vacuum
|
Ideal for high throughput
|
|
The MyoDynamics Muscle Strip System - 840MD represents a state-of-the-art 4-channel muscle strip system for intact muscle or muscle strips of up to 30 mm in length. The easy-to-use system allows the muscle physiologist to perform isometric, eccentric, and concentric contractions protocols performed by the build-in motors in a precise manner under a range of conditions, including electric field stimulation.
The system allows for four separate baths to run simultaneously and independently from each other. The system gives the flexibility to program each bath individually and initiate ad stop protocols independently from the other baths. Each muscle bath unit, made of aluminum, features a stainless steel chamber. The tissue mounting supports are positioned in the chamber, with one side attached to the force transducer and the other to a combination manual positioner screw and a motorized micropositioner. The manual positioner allows the accurate preload/base tension setting, while the motorized micropositioner permits the user to stretch (Eccentric)/relax (Concentric) the muscle according to user-defined settings. The sensitive force transducers provide measurements of contractile forces. Mounted tissue can be stretched and relaxed, defined by the user with a minimum distance of 10µm up to 11mm and a maximum speed of 11mm/sec. The 840MD comes with a controller software that enables autonomous experimentation. The software includes 30+ commands that allows parameters to be set for motor speed, pull range, force change and more. This also enables eccentric experimentation where the motors can start at the moment of muscle strip contraction. Stimulation electrodes built into the chamber cover (optional - various types) can activate the muscle via field stimulation from the DMT Stimulator. The 840MD has input and output trigger functions to activate the build-in motors by the DMT stimulator or visa versa. This system is well suited for studies involving muscle reactivity and fatigue experiment connected to neuromuscular disorders such as muscular dystrophy, metabolic, ataxia, and myofibrillar myopathies. Multiple units can be arranged side-by-side to facilitate high-throughput screening, such as drug testing or experiments requiring the separation of muscle preparations in individual baths. |
Related Products:
|
|
Muscle Strip Chamber# Eccentric and concentric contractions # Control and measurement of length and isometric force # Direct or field stimulation # Up to 30mm muscle strip length # Acid resistens stainless steel chambers # Ideal for muscle reactivity and fatigue testing |
Interface Unit# Integrated heating, gassing, & drainage # Selectable force range (mN) # Intregreted calibration procedure # Intuitive touch-screen interface menus # Compact design / small foot |
|
|
Electrophysiological Studies -
General Protocol Types; # Dystrophic/mechanome affected muscles # General physiological examination of diseased and healthy muscles subjected to an intervention # Metabolic affected muscles – Glycolysis /glycogen decomposition # Metabolic affected muscles – Fatty acid conversion # Ion channel defects – force affected # Ion channel defects – indirect force affected # Myofibrillary myopathies |
Provided by courtesy of
Dr. Thomas Krag, Copenhagen Neuromuscular Center |
Coming soon...
|
Specifications:
Chamber Chamber suction Chamber cover Chamber gassing Chamber size Chamber material Chamber temperature range Force range Force resolution Max. segment length Min. segment length Max. micrometer reach Max. micrometer step Motor speed Resolution Speed tolerance Min. resolution of motor Distance tolerance Motor control Analogue outputs Analogue output range Output impedance Digital input Voltage range Digital output Air Connection Transducer Data:
Max. Range Operating temperature Frequency range Active cooling with water:
Amount of cooling water Max. pressure Chamber temperature resolution Chamber temperature stability Physical Data:
Voltage Dimensions Net Weight Ambient temperature |
Four individual chambers Manual or automatic Supplied with connections for gassing Individually controlled per chamber Standard 8 ml, max. 15 ml Stainless steel Ambient - 40°C ± 200, 400, 800 or 1600 mN 0.1 mN 30 mm 2 mm 12 mm (manual) 11 mm (motor) 0.5 - 12 mm/sec. 0.1 mm/sec. 0.5% 10 µm ± 15 µm User defined protocols 4 BNC connectors ± 2.5 V <200 Ohm Two ports per chamber on the back panel Voltage range 5-24 VDC, Min. pulse length is 5 ms, Galvanically isolated Two per chamber on the back panel, Voltage range max. 24 VDC, Max. current is 30 mA, Min. pulse length is 10 ms, Galvanically isolated Max. 10 bar
± 1600 mN 15 - 40°C 0 - 20 Hz 50 - 300 ml/min. 0.5 bar 0.1°C ± 0.2°C 100-240 VAC to 24 VDC 49 x 30 x 17 cm (LxDxH) 9 kg 15 - 30°C |
|
Need-to-have:
|
Nice-to-have:
|
