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More about
MUSCLE STRIPMYOGRAPHY
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Basic Tissue Properties
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Pharmacology & Physiology
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Pathology & Phenotyping
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Further Possibilities
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Systems for striated muscle are the newest additions to the DMT product line, and we are actively developing new models. Our goal is to provide researchers with specialized, high-quality research instruments as well as multi-chamber screening systems. In these systems, pieces of solid muscle are clamped between mounting support and a force transducer.
Striated muscle, in contrast to smooth muscle, typically requires an electrical current or excitation to initiate contraction. It operates at an optimized length or preload. The contractions are often much faster than those found in smooth muscle and require robust force transducers with high fidelity. With analysis, the contractions are often transient, and specialty software is needed to analyze the tissue response for both contraction and relaxation parameters.
DMT allows for a variety of mounting options in these systems, some based on customer requests. Striated muscles such as cardiac and skeletal muscle can be studied combined with stimulators that can deliver enough power to excite this tissue in a reproducible way.
There is also much research investigating the molecular basis of muscle contraction. Measurement of force in a skinned muscle preparation is the preferred method to allow investigator control over the contractile unit's environment and composition. The measured forces are then much smaller and require.
Striated muscle, in contrast to smooth muscle, typically requires an electrical current or excitation to initiate contraction. It operates at an optimized length or preload. The contractions are often much faster than those found in smooth muscle and require robust force transducers with high fidelity. With analysis, the contractions are often transient, and specialty software is needed to analyze the tissue response for both contraction and relaxation parameters.
DMT allows for a variety of mounting options in these systems, some based on customer requests. Striated muscles such as cardiac and skeletal muscle can be studied combined with stimulators that can deliver enough power to excite this tissue in a reproducible way.
There is also much research investigating the molecular basis of muscle contraction. Measurement of force in a skinned muscle preparation is the preferred method to allow investigator control over the contractile unit's environment and composition. The measured forces are then much smaller and require.
