SERVICE & DEVELOPMENT
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MYOGRAPH SERVICE CHECK Keep your myograph system in top shape to ensure optimal performance. It is recommended to have a myograph system serviced every 1-2 years depending on usage.
The service check consists of; System dismantle, part cleaning, assembly, lubrication temperature re-compensation of transducers, calibration, functional system test, documentation. |
DESIGN & ENGINEERINGOur staff, equipt with state of the car CAD/CAM, design software, 5-axis CNC machines can help you get the ideal system for your application. Weather thought, a sketch or mechanical drawing, we can help you get a prototype, design and materials, and determine the best solution for the application
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CUSTOM FABRICATIONThis system was custom-made for molecular studies that focus on the contractile proteins and force development signal transduction research.
Key features of this custom-made system are very low volume baths for skinning or permeabilizing small muscle preparations and moving them smoothlybetween different cell internal solutions that mimic intracellular environments. The system has four independent heated channels. Individual micro-stirring of the small volumes, heating and cooling capability for Q10 studies, and a very sensitive force transducer (μN sensitivity) that is robust to withstand handling. |
Permeabilization will benefit pharmacological and physiological studies into the signal transduction cascade leading to force generation and studies of the calcium-sensitivity of force. Skinning will benefit physiological and biophysical studies in the molecular mechanisms of force development and actin-myosin interaction. ,
The system wasmade for and in collaboration with the laboratory of Prof. Avril Somlyo, University of Virginia, USA.
The system wasmade for and in collaboration with the laboratory of Prof. Avril Somlyo, University of Virginia, USA.
CUSTOM FABRICATIONThis custom-made system is for skeletal muscle fibers and used in the study Phenol increases intracellular [Ca2+] during twitch contractions in intactXenopus skeletal myofibers.
The system were developed for Dr. M. C. Hogan, University of California, USA. |
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