Organ Bath System - 820MOOptimized Isometric Force Measurement for Isolated Smooth, Cardiac, and Skeletal Muscle Preparations
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Multi-Channel Capability
Handles multiple tissue samples simultaneously, increasing throughput and efficiency |
Precision and Sensitivity
programmable force transducers and selectable force ranges, allowing for more precise and sensitive measurements |
Durability
Made from acid-resistant stainless steel, the DMT system prevents lipid and compound adhesion, ensuring longevity and minimal maintenance |
Ease of Use
With built-in oxygenation, buffer drainage, and heating, the DMT system is designed for easy setup, maintenance, and cleaning. |
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The Organ Bath System - 820MO is a fully integrated platform designed for high-precision contractile studies using isolated smooth, skeletal, or cardiac tissue. The system maintains tissue viability in a carefully controlled environment, where segments are submerged in a heated, continuously oxygenated perfusate. Isometric force transducers capture even subtle changes in contraction and relaxation, ensuring reliable and reproducible data.
With a flexible range of mounting options, the 820MO accommodates a wide variety of preparations - including aortic rings, tracheal tissue, veins, uterine strips, colon, ileum, diaphragm, and more. Tissue is immersed in an >8 mL chamber filled with temperature-controlled perfusate. One end is secured to a sensitive isometric force transducer, while the other is connected to a precision micrometer that enables accurate preload adjustment and fine control of resting tension. After mounting and equilibration, researchers can easily establish length-tension relationships and assess tissue responsiveness. During experiments, the muscle length is held constant, and compounds can be added directly to the chamber for functional evaluation. The 820MO eliminates the need to physically swap transducers by offering selectable force ranges, allowing users to optimize sensitivity across different tissue types. The rectangular chamber is constructed from acid-resistant stainless steel, minimizing lipid adhesion and ensuring long-term durability. Regardless of whether rings or long tissue strips (>20 mm) are used, mounting is straightforward. Chambers can be removed and placed under a dissection microscope for rapid, precise setup. For protocols requiring electrical stimulation, the system supports both field and direct stimulation via optional electrode configurations. The robust chamber design and choice of materials significantly reduce maintenance demands. Preparing the system for use is fast and uncomplicated, and post-experiment cleaning typically requires only a few water rinses. The aluminum and stainless-steel components resist corrosion and are engineered for sustained heavy use without the need for elaborate cleaning procedures. The DMT Organ Bath is also compatible with the Automatic Buffer Filler System (625FS), making it an excellent solution for high-throughput screening, drug testing, or experiments where multiple isolated tissues must be maintained in parallel under consistent conditions. |
Related Products:
System Comparison |
Large Organ Bath Chamber# Multifunctional purpose - tubular or strip segments # Acid resistant stainless steel chamber (avoid lipids/compounds sticking) # Larger vessel capability # Ring mounted tissue >500µm # Strip mount muscle <45mm 
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Organ Bath Chamber# Multifunctional purpose - tubular or strip segments # Acid resistant stainless steel chamber (avoid lipids/compounds sticking) # Ring mounted tissue >500µm # Strip mount muscle <20mm # Low chamber volume 
Interface# Adjustable force range # Integrated heating, gassing, & drainage # Direct data streaming (LabChart) # Intregreted calibration procedure # Intuitive touch-screen interface menus # Compact design / small footprint |
Comparison to traditional systems
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DMT Organ Bath 820MO |
Other Organ Baths |
Easily perform a diverse range of experiments |
Yes Change from vessel rings to muscle strips without changing the transducer. |
No A series of separate transducers are generally required. |
All-in-one system |
Yes Convenient all-in-one system. |
No Separate components are required. |
Portable and robust |
Yes Compact and robust. No glass to break. Easily moved on or off the bench. Can be shared with other researchers. |
No Fragile and time-consuming to pack away. Expensive glass is easily broken. |
Direct data streaming |
Yes Save data directly to your computer using MyoDAQ Acquisition. |
No Must be used with data acquisition hardware. |
Reduces consumable costs including drugs |
Yes Due to the small chamber volume, you save up to 80% in drug cost, depending on the chamber size currently used. |
No Chamber sizes vary significantly. Larger chambers require more drugs or reagents. |
Easy to clean |
Yes Easy clean rectangular stainless-steel chambers. |
No Double jacketed glass, plastic chambers, and fragile difficult-to-remove parts. Detailed cleaning procedures are the norm. |
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Chamber:
Chamber volume (min): Chamber volume (max): Chamber(s): Chamber material: Tissue size - ring mount: Tissue size - strip mount: Vessel normalization: Micrometer resolution: Mounting type: Temperature:
Range: Resolution: Stability: Heating: Transducer:
Output reading: Range: Resolution: Force calibration: Output:
Data communication: Analogue output channels: Analogue output range: *Refers to 820-XL Chamber |
4.0 ml (10 ml*) 8.0 ml (16 ml*) 4 Acid resistant stainless steel 500µm -19mm (500µm - 30mm*) 1mm -19mm (1mm - 45mm*) Manually 0.01 mm Pins and Clamps
15.0 to 50.0 °C 0.1 °C ±0.2 °C Yes mN or g ±200/±400/±800 or ±1600 mN 0.01 mN Yes USB 2.0 4 ±2.5 V |
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