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​Pressure Myograph System - 114P

Study the pharmacological effects of drugs and other vasoactive compounds on small isolated vessels, veins or other vessels under near-physiological conditions
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Acid resistant stainless steel for avoiding lipids sticking
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Ideal for pressurized arteries
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Direct data streaming to
​MyoVIEW Live Tracking
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Reliable, flexible & trusted
The Pressure Myograph System - 114P is used to measure small arteries, veins, and other vessels physiological function and properties.  It allows studying pharmacological effects of drugs and other vasoactive compounds on small isolated vessels under near-physiological conditions.  A small, intact segment of an artery or vein is mounted onto two small glass cannulas and pressurized to a suitable transmural pressure. The near-physiological condition permits the investigation of myogenic responses, flow-mediated dilation, and pharmacological agent testing, either to the superfusate or luminal solution.

A built-in heating system maintains the chamber temperature, eliminating the need for continuous and often costly superfusion. The chamber cover includes ports for superfusion, rapid draining and filling, cumulative addition of drugs, and oxygenation. To facilitate cleaning, the chamber is made of acid-resistant stainless steel. 

The state-of-the-art Pressure Myograph software MyoVIEW will collect data such as vessel wall thickness, changes in vessel and lumen diameter, intravascular pressure, and a host of other calculated parameters, such as shear stress and vascular resistance, setting pressure or perfusion myography apart from standard organ bath techniques. 

As an option, the FlowMeter - 162FM can be added to the system to measure flow between 15-4000μl/min. 
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Related Products:​​
  • MyoVIEW Acquisition
  • Computer Package (Desktop)
  • Inverted Microscope 
  • Stage Micrometer 
  • Camera – USB 
  • Vacuum Package
  • Heating Bath Circulator
  • Dissection Stereo Microscope 
  • Cold Light Source 
  • Dissection Tool Kit​
  • FlowMeter - 162FM 
  • Nylon Suture ​​
  • Gas supply manifold- 4-channel 
  • Peristaltic pump 
  • Cannulas - Stainless Steel 
  • Cannulas - Glass (60µm-160µm)
  • Service & Maintenance Agreement 
  • Extended warranty +3 years 
Quote Request

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​Myograph Chamber

​# Constant transmural pressure or luminal flow situation
# Visualization of vessel through optical base window
# Longitudinal force measurements
# Vessel diameter >30µm and <10mm length
# In-line pressure transducers
# ​XYZ alignment of pressurized vessel
# Acid resistant stainless steel chamber

Interface Unit

​# Integrated buffer reservoir (heated)
# ​Direct data streaming
# Integrated heat control
# Integrated force and pressure calibration procedure
# ​Intuitive touch-screen menus
# Compact design / small footprint
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​​Diameter Tracking Software

​​# Live detection
# Multiple zones for edge detection
# Multiple scanlines for accurate measurements
# Event markers and tracking
# Real-time calculations of diameter, wall thickness, cross-
    sectional area, flow, vascualr resistance, shear stress
​    and more

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"We really appreciate the excellent technical customer service and high degree of professionalism. Its so good for us to know that we can rely on DMT."
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​Dr. Rhian Touyz

Executive Director and Chief Scientific Officer
/
​Research Institute of McGill University

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  • Product Videos
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  • Related Products
<
>
  • SYSTEM INTRODUCTION
  • SETTING UP
  • ​CALIBRATION
  • CLEANING & MAINTENANCE
  • EXPERIMENTAL SETUP
Chamber:
​
​Chamber volume (min):
Chamber(s):
Chamber material:
Vessel size:
Vessel alignment:
Micrometer resolution:
Mounting type:
Temperature:
​
Range:
Resolution:
Stability:
Heating:
Transducer Force:
​
Output reading:
Range:
Resolution:
Force calibration:
Transducer Pressure:
​
Output reading:
Range:
Pressure stability:
Resolution:
​Force Calibration:

RESERVOIR:
Heated:
Capacity:
Pressure circuit:
​Air inlet:
Output:
​
Data communication:
Analogue output channels:
Analogue output range:

​3.1 ml
1
Acid resistant stainless steel
>40 µm
X, Y, Z
0.01 mm
Cannulas
​​
​15.0 to 50.0 °C

0.1 °C
±0.2 °C
​Yes

​mN 
±200 mN
0.01 mN
Yes

mmHg
0 - 250 mmHg
±0.5 mmHg
0.1 mmHg
Yes

Yes
250 ml
Closed
​​1 bar (max)

​USB 2.0
4
​±2.5 V

MYOGRAPH SYSTEM - 112PP/114P USER MANUAL VOL. 3.1
MYOGRAPH SYSTEM - 112PP/114P USER GUIDE VOL. 3.0
​
MyoVIEW ACQUISITION USER MANUAL VOL. 5.0
Calibrate Pressure Transducers​
Check Transducer Functionality (Pressure)
Replace Cannulas
Replace the Cover Glass
Replace the Pressure Transducers
Check for a Pressure Leak

More...
Need-to-have:
  • MyoVIEW 5 Acquisition (#300598)
  • Inverted Microscope - Zeiss Axio Vert A5 (#400410)
  • or Nikon Eclipse Ts2 (#400409)
  • or DMT Microscope Package (#101033)
  • Camera – Monochrome (#300617) – necessary if sold with Zeiss or Nikon
  • Stage Micrometer (#400449) - necessary if sold with Zeiss or Nikon
  • Computer Package (Desktop) (#101022)
  • Vacuum Package - 110V (#101018), 220V (#101052)
  • Open Heating Bath Circulator- Water bath 110V (#400738), 220V (#400740)
  • Dissection Stereo Microscope – Zeiss Stemi 305 (#400484)
  • Light Source CL6000 LED- Swan-neck (#400794)
  • ​Dissection Tool Kit (#101017)
Nice-to-have:
  • FlowMeter - 162FM (#300144)
  • Installation Kit (#300639)
  • Gas Supply Manifold- 4-channel (#300295)
  • Gas Supply Manifold - 10-channel (#300345)
  • Peristaltic pump – 2-Channel (#400422)
  • Pressure Transducer (#300055)
  • Cannulas Stainless Steel (300μm-1200μm)
  • Cannula Pack (glass) (60μm-160μm)
  • Glass cutter (#400675)
  • Service & Maintenance Agreement (5yr) (#101054)
  • Extended warranty +3 years (#101034) 
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Data Sheet

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Citations Google Scholar

WIRE MYOGRAPH SYSTEMS
​Single Wire Myograph System - 320A
Confocal Wire Myograph System - 360CW
​Dual Chamber Wire Myograph System - 420A
Multi Myograph System - 620M
Automated Multi Myograph System - 630MA
​​
​​ORGAN BATH SYSTEMS
Multi Myograph System - 620M
Organ Bath System - 751MT
Organ Bath System - 820MO
​
​MUSCLE STRIP SYSTEMS
Tissue Puller - 560TP
MyoDynamics Muscle Strip System - 840MD
​
​​​PRESSURE MYOGRAPH SYSTEMS
Pressure Myograph System - 110PXL
Pressure Myograph System - 112PP
Pressure Myograph System - 114P
Pressure Myograph System - 114PB
Pressure Myograph System - 114PN
SUPPORT
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​
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© 2025 Danish Myo Technology A/S
  • Products
    • Muscle Strip Systems >
      • Tissue Puller System - 560TP
      • MyoDynamics Muscle Strip System - 840MD
    • Organ Bath System >
      • Organ Bath System - 751MT
      • Organ Bath System | 820MO
    • Pressure Myograph Systems >
      • Pressure Myograph System - 110PXL
      • Pressure Pulsation Myograph System - 112PP
      • Pressure Myograph System - 114P
      • Pressure Myograph System - 114PB
      • Pressure Myograph System - 114PN
      • Pressure Myograph System - 120CP
    • Wire Myograph Systems >
      • Single Wire Myograph System - 320A
      • Confocal Wire Myograph System - 360CW
      • Dual Wire Myograph System - 420A
      • Multi Myograph System - 620M
      • Automated Multi Myograph System - 630MA
    • Myograph Software >
      • MyoNORM
      • MyoDAQ Acquisition
      • MyoVIEW 5
      • MyoPULSE
    • Accessories & Parts >
      • Buffer Filler System
      • Dissection & Mounting
      • FlowMeter - 162FM
      • Stimulators >
        • Stimulator - CS4+
        • Stimulator - CS8
      • Transducers
  • Support
    • Guides, Videos & More >
      • Product Videos
      • Guides & Manuals
      • Protocols/Articles
      • Software Downloads
      • How To Videos
    • Myograph Training/Installation
    • System Maintenance
  • Insights
  • About us
  • Contact