Dr. Eric Belin de Chantemele: Advancing Cardiovascular Research with a Focus on Women’s Health4/17/2025
 Dr. Eric Belin de Chantemele, a Professor of Medicine at the Vascular Biology Center at Augusta University, has dedicated his research to understanding the complex relationship between obesity, hypertension, and cardiovascular disease, particularly in women. His work explores how lipid deficiency and lipo-dystrophy in mice impact vascular function, with a specific focus on how the absence of fat affects cardiac health. Interestingly, his initial research was inspired by studying the effects of spaceflight on cardiac disease in mice, which eventually led him to uncover critical insights about obesity-related hypertension.
One of Dr. Belin de Chantemele’s most surprising discoveries came while working with a mouse model deficient in alpha-1B receptors. When he ran out of male mice and had to shift focus to female mice, he discovered that female mice displayed worse vascular function. This finding was unexpected but he believed in the data, which led to his groundbreaking research on leptin, a hormone that regulates estrogen—resulting in his most cited paper to date. His research holds immense promise for the future, with the ultimate goal of developing targeted treatments for cardiovascular disease in women. Dr. Belin de Chantemele hopes that his work will lead to more personalized therapies that address the unique cardiovascular challenges faced by women, closing the gap in treatment outcomes. A long-time user of DMT equipment from his postdoc in France, Dr. Belin de Chantemele praises the reliability and ease of use of the systems, noting that his lab operates seven DMT wire systems daily. This dependable technology has been instrumental in facilitating his research and ensuring consistent results. When reflecting on his career, Dr. Belin de Chantemele is most proud of the impact he’s had on the next generation of researchers. Many of his trainees have transitioned to faculty positions, received prestigious awards, and, in 2024 alone, three of his students were awarded fellowships while another three secured R01 grants. Like many in his field, Dr. Belin de Chantemele faced significant challenges early in his career, particularly in securing his first R01 grant, which took three submission cycles to obtain. His advice to aspiring researchers is simple yet powerful: “Be persistent, believe in your data, and don’t be afraid to fail.” Through his commitment to research, mentorship, and innovation, Dr. Belin de Chantemele continues to shape the scientific community and pave the way for future breakthroughs in cardiovascular health.  🔧 New Video Alert! 🎥
Need to change a force transducer on a 630MA? We've got you covered! Our latest YouTube video walks you through the process step by step, making it easy to keep your setup running smoothly. Watch now and ensure your experiments stay precise and reliable! ⬇️ 📺 Watch Now: https://youtu.be/zrWNE8Dvvz4 #LabTech #ForceTransducer #HowTo #DMT  We had the opportunity to conduct a hands-on training and install of the 620M Wire Myograph System with a Vacuum Package with Nicha Boonpattrawong.
Dr. Boonpattrawong's impressive journey spans from earning her degree at the University of Toronto to groundbreaking research in cardiometabolic disease and ovarian cancer at BC Children’s Hospital and UW-Madison. Now, as she launches her own research program in metabolic physiology of cancers and metabolic diseases, our DMT equipment will play a key role in helping her characterize metabolic reprogramming in disease models and identify potential treatment targets. We’re excited to support her innovative research and look forward to seeing the incredible discoveries ahead! 💡  We are thrilled to be a Specialty Sponsor at the 2025 NAA Conference, taking place on June 27-28 in Philadelphia, Pennsylvania!
 We just released a step-by-step MyoVIEW tutorial to help you streamline your workflow and ensure precision every time. Whether you're new to MyoVIEW or just need a quick refresher, this video has you covered!
📺 Watch now: https://youtu.be/COpj_mEN-Xk Let us know what you think in the comments! #Myoview #HowTo #LabEfficiency  We had the opportunity to conduct a hands-on training session of the 112PP Pressure Myograph System at Thiago Bruder's lab at the University of South Alabama.
Their research is focused on understanding how endothelium-derived molecules influence vascular remodeling in conditions such as hypertension and vasculitis. Using the 112PP system, they’re diving deep into exploring vascular function under physiological and pathological conditions. A big thank you to Thiago and the entire team for their enthusiasm and commitment to advancing vascular research. Looking to enhance your vascular research? Contact us to learn how our pressure myograph systems can support your work! See more... #VascularResearch #Hypertension #PressureMyograph #Endothelium #CardiovascularHealth #ResearchTraining #DMT  New Training Video Series Alert! 🎥
We’re excited to release the 112PP Pressure Myograph Training Video Series, designed to help you master every step of your vascular research journey! From setup to advanced techniques, these videos showcase how to get the most out of your 112PP system for groundbreaking discoveries. 💡 Whether you’re new to pressure myography or looking to refine your skills, this series is your go-to guide for precision and innovation. Ready to elevate your research? Check out the series now and let us know what you think! For more information: https://www.dmt.dk/pressure-pulsation-myograph-112pp.html #DMT #PressureMyograph #VascularResearch #TrainingMadeEasy #InnovationInScience  🎄✨ Happy Holidays from DMT! ✨🎄
Thank you for being part of our journey in advancing science. Here’s to a successful and innovative New Year! 🧪🎉  Last week, our Senior Scientific Product Specialist Larry Agbor, Ph.D, M.S had the opportunity to conduct a hands-on training session at the Rhian Touyz, MBBCh, PhD, FRCP, FRSE, FCAHS, FMedSci Laboratory at McGill University. The session provided researchers with in-depth guidance on maximizing the system’s capabilities to advance their vascular studies using the 114p pressure myograph system.
Thank you, McGill, for the warm welcome. We’re looking forward to seeing how this new knowledge and technology will fuel future discoveries! For more information, visit: https://www.dmt.dk/pressure-myograph-114p.html #Training #VascularResearch #CustomerSupport #McGillUniversity #ScientificInnovation  🔬 This week, our product specialist Bill Wisniewski visited Dr. Yabing Chen’s lab at Oregon Health & Science University for an in-depth training session on the 620M & MyoDAQ! It was a great opportunity to collaborate directly with the lab team, diving into advanced features and techniques to help streamline their research and enhance their workflow.
Thank you to the team Erandi Velazquez-Miranda, Ph.D., Marco Bravo, Yong Sun & Zhehao Zhu for the warm welcome and engaging session. We’re excited to support the impactful work being done at OHSU! For more information, visit: https://www.dmt.dk/multi-myograph-620m.html // https://www.dmt.dk/myodaq.html #LabTraining #OHSU #ScientificResearch #InnovationInAction  Jessica Rippamonti, a Graduate Research Assistant at the University of North Texas, is at the forefront of groundbreaking research focused on patent ductus arteriosus (PDA), a condition in which a blood vessel vital to the development of babies in utero (the ductus arteriosus) is stuck open after birth. This is an issue affecting a significant percentage of premature babies. Once considered a severe and potentially deadly condition, the PDA can be a challenging issue in neonatal care. Jessica’s research is dedicated to understanding how this vessel can be manipulated, with the goal of developing less invasive treatments that reduce the impact on these vulnerable infants.
The ductus arteriosus (DA) plays a crucial role in organ development and is present in all land vertebrates, making it an evolutionarily conserved feature. Jessica’s work primarily involves studying this vessel in chicken embryos. Her experiments are conducted using a DMT wire myograph, a “versatile tool” that has allowed her to explore everything from the arteries of embryonic chickens to those of 4-5 year old alligators. This versatility has been essential in investigating the various pathways that can influence the DA, particularly in finding ways to close the vessel by enhancing actin fibers or even open the vessel in specialized circumstances. Despite the field being relatively small with limited publications, Jessica is passionate about scientific communication. She values the opportunity to present her findings at specialized meetings and enjoys teaching others about the significance of her work. Her ultimate goal is to make people care about this crucial area of research. Jessica’s advice to aspiring researchers is to "be gritty and persevere." She encourages them to appreciate the journey, even if the next step isn’t the final goal they envision. Her dedication and innovative approach are paving the way for new treatments that could significantly improve the lives of premature infants.  Our Sr Scientific Product Specialist Larry Agbor, Ph.D, M.S recently completed a successful installation of pressure and wire myograph systems at the University of Colorado Denver. These advanced tools will enable groundbreaking research into vascular function and physiology. We’re thrilled to support such a prestigious institution in pushing the boundaries of scientific discovery!
Thank you to the team at CU - Zachary Clayton, PhD & Branden Nguyen for choosing us, and we can't wait to see the incredible research that will come from this collaboration! 👩🔬🧑🔬  We believe in the power of collaboration and innovation.
As the 51th European Muscle Conference aligns with our commitment to advancing scientific research and development, we are pleased to be a supporting sponsor. Learn more: https://www.emc2024ljubljana.com Tired of complicated and expensive acquisition software that offers multiple disciplines that are never used. Look no further… MyoDAQ Acquisition is here and offers dedicated usage.  Basic & Simple to Use: Designed with simplicity in mind, making is easy for anyone to use, regardless of expertise.
Pay Only for What You Need: You only pay for the functionalities needed for myography, ensuring cost-effectiveness and efficiency. Discover the power of MyoDAQ and transform your data acquisition process to simplicity. Request your FREE trial version today!  DMT MyoNORM is a simple multi-platform free application that allows you to calculate optimal length/tension relationship of small arteries.
In this "How To" video, you will be learning about the proper normalization procedure for vessels using the DMT MyoNORM Software. Product Link: MyoNORM To learn more visit our Resources Page  Dr. Michael Hill: A Pioneer in Vascular Research Dr. Michael Hill has dedicated his career to uncovering the mysteries of small blood vessels and their mechanical properties, focusing on how these properties influence vascular function and overall health. His research is particularly vital for understanding the "myogenic response," a mechanism by which blood vessels react to pressure changes, and its implications for conditions such as diabetes and vascular stiffness. Inspiration & Research Impact Dr. Hill's inspiration to study the mechanical properties of small blood vessels stems from his desire to understand how blood flow is regulated, especially in diabetic patients. His research sheds light on how blood vessels respond to mechanical stimuli and how these responses affect vascular health. By studying the myogenic response, Dr. Hill aims to develop better treatments for diabetes and arterial stiffening, a common issue that can lead to severe health complications. Dr. Hill's work significantly advances the scientific community's understanding of vessel function, particularly the relationship between tension, pressure, and vessel diameter. This knowledge is crucial for developing strategies to treat arterial stiffening, which can have widespread health benefits. By improving our understanding of how blood vessels function and respond to mechanical stress, Dr. Hill's research holds promise for creating more effective treatments for cardiovascular diseases. Exciting Projects & Discoveries Throughout his research, Dr. Hill has encountered several unexpected findings. One of the most surprising was the variation between arteries within different vascular beds. His studies revealed that a 100-micrometer vessel does not function the same across various parts of the body. For example, skeletal muscle arteries and mesenteric arteries have elaborate protein structures on their exteriors, which can significantly impact their function. In contrast, cerebral arteries, protected within the skull and subjected to less external forces, lack these protein structures. These insights were made possible through advanced confocal imaging and myograph force measurement experiments. One of the most recent and exciting projects in Dr. Hill's lab involves research conducted by Dr. Luke Sun, a member of his team. Dr. Sun's work on cerebral vessels has shown that these cells within these vessels quickly remodel in response to pressure changes by changing the distribution of contractile proteins and adhesion molecules, a discovery that has already resulted in a published paper. This project exemplifies the innovative and impactful research taking place under Dr. Hill's guidance. A Message for Aspiring Researchers In his time as a researcher and in related roles such as associate editor for the journal Metabolism, Clinical and Experimental, Dr. Hill has worked with many up and coming researchers looking to make their mark in the cardiovascular field and offers invaluable advice: never give up. Rejected grants and publications are part of the journey, and it's crucial to listen to feedback and build on it. He encourages young researchers to publish their findings and write grants to establish their presence in the scientific community. Dr. Michael Hill's contributions to vascular research are invaluable, providing insights that have the potential to improve societal cardiovascular health. His dedication and innovative approach has allowed for collaboration with researchers worldwide, exemplifying the impact that persistence and passion can have in the scientific community. These qualities are evident in his words: "It's the only career where you get paid to be a treasure hunter."
 🚀 Exciting News! We're thrilled to announce the relaunch of our 560TP Tissue Puller System!
The 560TP is a user-friendly tensometer designed for quick and easy determination of tensile strength in tissues. With the MyoPULL software, users can swiftly evaluate characteristics such as compliance, stress-strain, and fatigue through real-time plotting of the length-tension relationship of the sample tissue. This advanced system streamlines your research process, providing accurate and efficient results. Get ready to elevate your tissue analysis to the next level!  We had a wonderful visit with Benjamin Smood, MD at Penn Medicine, University of Pennsylvania Health System! Excited to share the successful installation of the 620M Wire Myograph paired with our Buffer Filler System. This state-of-the-art equipment will empower researchers and students to delve deeper into vascular physiology, advancing our understanding of cardiovascular health and disease. Kudos to our Sr Scientific Product Specialist, Larry Agbor, Ph.D, M.S for aiding in the installation!
#WireMyography #Research #CardiovascularScience #PennStateUniv  We are pleased to announce the launch of our new proprietary data acquisition software, MyoDAQ! MyoDAQ offers a simplified data acquisition application intended for use with DMT wire myographs and organ bath systems. This software provides a streamlined, user friendly approach for data collection and analysis.
By highlighting only necessary features, researchers experience improved ease-of-use, better navigation and easier control for data analysis. To learn more about this software, visit https://www.dmt.dk/myodaq.html or contact a DMT representative! #dataanalysis #dataacquisition #wiremyography #organbath  Having a great first day at The American Physiology Summit @APSPhysiology. We love seeing a lot of familiar faces and connecting with everyone. Make sure to stop by our booth (#520) and say hello. We look forward to seeing you! #APS2024 #WeArePhysiology
 Just one week until the American Physiology Summit! We look forward to attending and connecting with you all there. Stop by our booth (#520) for the latest updates on our myograph systems and get a sneak peek of our new and simplified data acquisition software, developed explicitly for organ bath and myograph systems. See you soon!
#APS2024 In a few weeks, at the American Physiology Summit, stop by our booth (#520) and get a sneak peek of our new and simplified data acquisition software, developed explicitly for organ bath and myograph systems.   The Pressure Myograph System - 110PXL is used to measure large arteries, veins, and other vessels physiological function and properties. The 110PXL chamber, in combination with low-power objectives, can be used for the study of large artery reactivity and/or compliance by measuring diameter changes under physiological pressures, which are precisely controlled through the system interface.
The system comes with mounts of 1.5mm, 3mm, and 4mm for mounting vessels between 1.5-6.0mm. There is no force transducer on the standard chamber, but it can be added. This system is a great option for expanding pressure myograph capabilities!  In this video, you will be learning about how to grease important mechanical parts on the Multi-Myograph System 620M.
Product Link: Multi-Myograph System 620M To learn more visit our Resources Page For more information visit us at www.dmt.dk or email [email protected] to speak to a representative.  Introducing the 820XL chamber! This robust organ bath chamber offers myograph users a larger tissue capability while still maintaining the compact features of the organ bath interface.
Users will be able to work with rings larger than 500µm and strips up to 45mm in length, giving an ideal range for those experimenting with larger vessels. For more information on the 820XL Chamber, visit: https://www.dmt.dk/organ-bath-820mo.html |
