ALL DMT WIRE MYOGRAPH SYSTEMS

​Investigate small vessels in the form of morphology and responsiveness to hormones and other agonists with the Wire Myograph Systems from Danish Myo Technology A/S. Read more about the different Wire Myograph Systems below to get an in-depth insight into the various types of systems and their features and benefits.  ​​

Single Wire Myograph System - 320A

Single Wire Myograph System - 320A is ideal for studying a single vessel with a diameter of 60 μm - 3 mm. The vessel is mounted as a ring preparation by threading it over two parallel stainless steel wires and securing the wires to two supports or "jaws".

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Dual Wire Myograph System - 420A

The Dual Wire Myograph System - 420A is designed for simultaneous testing of two vessels with diameters of 60 μm - 3 mm, independently. The vessels are mounted as ring preparations by threading them over two parallel stainless steel wires and securing the wires to two supports or "jaws". One support is attached to a precision micrometer, allowing manual control of vessel circumference and stretch. The other support is attached to a force transducer for measurements of force/tension development.

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Auto Dual Wire Myograph System -520A

The Auto Dual Wire Myograph System - 520A is designed for simultaneous testing oftwo vessels with diameters of 60 μm - 3 mm, independently. The vessels are mounted as ring preparations by threading them over two parallel stainless steel wires and securing the wires to two supports or "jaws". One support is attached to a linear motor-driven micrometer, allowing automated control of vessel circumference and stretch. The other support is attached to a force transducer for measurements of force/tension development.​

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Multi Wire Myograph System - 620M
​

The Multi Wire Myograph System - 620M is the successor to our very popular 610M myograph system. This 4-channel multi myograph system is a highly sophisticated yet robust research instrument. It is an easy-to-use system for in vitro studies of small and large blood vessels, trachea or gut mounted as larger ring preparations (up to 10 mm).​

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Automated Multi Wire Myograph System - 630MA

Making it easier… the newly developed 4-channel system adds the ease of automating the normalization procedures so that calculations and preload tension is easily set. Following mounting and equilibration, passive length-tension relationships are determined by a standardized procedure. This allows the standardization of initial experimental conditions, an important consideration when examining pharmacological differences between vessels.

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​Confocal Wire Myograph System 
​- 360CW

The Confocal Wire Myograph System - 360CW is specially designed to provide very close optical access to the mounted artery or tissue segment, thereby allowing high resolution images of fluorescent dyes or markers by laser scanning confocal microscopy (LSCM). This system elegantly combines LSCM with artery myography to allow simultaneous measurements of isometric force and fluorescence. A perfect example are studies that correlate isometric contractions in an isolated, mounted blood vessel and intracellular Ca2+ measurements within the vascular smooth muscle cells.

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What is the difference between pressure myograph and wire myograph?

Both pressure myograph systems and wire myograph systems are widely used methods. The wire myograph system allows control and study of up to 4 vessels or tissue rings simultaneously. In addition, it is technically a bit more easier to use. They have an extensive set of custom add-ons and options to match your specific need. 

The pressure myography system is more physological than wire myography. It allows the study of small vessel function under near-physiological conditions of pressure and flow by digital tracking of diameter and flow in time.