​Wire Myograph Systems for Vascular Research

Measure isometric force in small arteries and vascular ring preparations with systems built for academic physiology workflows—whether you’re running deep mechanistic protocols, paired comparisons, confocal imaging, or higher-throughput concentration–response curves.
Not sure which system fits your prep? Use the quick guide below or compare models side-by-side.
Primary applications
  • Endothelium-dependent/-independent reactivity
  • Vasoactive pharmacology & CRCs
  • Mechanistic signaling studies (e.g., NO, prostanoids, Rho-kinase)
  • Vessel viability, wire mounting, normalization, and tension protocols
  • Imaging-coupled force recordings (model dependent)

Single Wire Myograph System - 310A

Best for: mechanistic physiology, maximum flexibility, one vessel at a time
Typical day: detailed protocols, complex interventions, extended equilibration
Why labs choose it
  • Ideal when your experiments are deep rather than high-throughput
  • Great “workhorse” setup for small vessel rings and precision force recording
    Good fit if you say: “We run one vessel at a time but we want pristine data and flexibility.”

Confocal Wire Myograph System - 360CW

Best for: imaging-first vascular research (confocal/fluorescence + force)
Typical day: simultaneous functional readouts and optical measurements
Why labs choose it
  • Designed for excellent optical access during force recordings
  • Enables imaging-coupled pharmacology and signaling workflows
    Good fit if you say: “Imaging isn’t optional—we need it built into the setup.”

Dual Wire Myograph System - 420A

Best for: paired comparisons (control vs treated, WT vs KO), efficient workflows
Typical day: two vessels in parallel under matched conditions
Why labs choose it
  • Perfect for studies where paired design boosts statistical power
  • Faster decision-making during experiments (you see both conditions at once)
    Good fit if you say: “We do a lot of head-to-head comparisons and want to stay efficient.”

Multi Wire Myograph System - 620M

Best for: higher throughput CRCs, screening, multiple conditions in parallel
Typical day: 3–4 vessels per run; multiple drugs or conditions per experiment
Why labs choose it
  • Speeds up concentration–response curves and multi-condition experiments
  • Great for busy labs that need more data per day without changing methodology
    Good fit if you say: “We’re running lots of CRCs and want more throughput.”

Automated Multi Myograph System - 630MA

Best for: high-throughput + standardization across users (automation)
Typical day: consistent normalization/preload across four vessels with less hands-on time
Why labs choose it
  • Reduces operator variability in normalization workflows
  • Especially helpful in multi-user labs, core facilities, and training environments
    Good fit if you say: “We want reproducibility and speed across different operators.”
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