DMT SINGLE MYOGRAPH SYSTEM 320A
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FEATURES & BENEFITS
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The new updated Single Wire Myograph System 320A from DMT is a part of the membership of the Wire Myographs product range. With the finger touch screen it has been designed to be very easy to use. Furthermore, the new Interface of the Wire Myograph System is prepared for the DMT Device Enabler allowing Automatic recognition of supported devices by LabChart. It also allows use of multiple devices simultaneously, correct units and ranges in LabChart channels but also recording of data into LabChart alongside a PowerLab.
The Single Wire Myograph System 320A developed by DMT is ideal for studying a single vessel with a diameter of 30 μm - 3 mm. The vessel is mounted as a ring preparation by threading it over two parallel stainless steel wires and securing the wires to two supports or "jaws". One support is attached to a precision micrometer, allowing manual control of vessel circumference and stretch. The other support is attached to a force transducer for measurements of force/tension development.
The preparation is mounted in a heated 10 ml acid-resistant, stainless steel chamber, which can be covered with a lid featuring ports for rapid suction/draining, refilling and bubbling of oxygen. The base of the chamber contains a window allowing morphological observation or fluorescence measurements on an inverted microscope. Typically, the preparation is kept in the heated vessel chamber in a physiological salt solution at 37°C, bubbled with oxygen where the vessels remain viable for at least 12 hours.
The Single Wire Myograph System 320A developed by DMT is ideal for studying a single vessel with a diameter of 30 μm - 3 mm. The vessel is mounted as a ring preparation by threading it over two parallel stainless steel wires and securing the wires to two supports or "jaws". One support is attached to a precision micrometer, allowing manual control of vessel circumference and stretch. The other support is attached to a force transducer for measurements of force/tension development.
The preparation is mounted in a heated 10 ml acid-resistant, stainless steel chamber, which can be covered with a lid featuring ports for rapid suction/draining, refilling and bubbling of oxygen. The base of the chamber contains a window allowing morphological observation or fluorescence measurements on an inverted microscope. Typically, the preparation is kept in the heated vessel chamber in a physiological salt solution at 37°C, bubbled with oxygen where the vessels remain viable for at least 12 hours.
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CHAMBER:
Chamber volume (min) Chamber(s) Chamber material Vessel size Vessel normalization Micrometer resolution Mounting type TEMPERATURE: Range Resolution Stability Heating TRANSDUCER: Output reading Range Resolution Force calibration OUTPUT: Data communication Analogue output channels Analogue output range |
4.2 ml 1 Acid resistant stainless steel >30 µm Manually 0.01 mm Jaws 15.0 to 50.0 °C 0.1 °C ±0.2 °C Yes mN ±200 mN 0.01 mN Yes USB 2.0 4 ±2.5 V |
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NEED-TO-HAVE
Data Acquisition - LabChart Pro (400106) Cable - USB 2.0 (400107) Computer Package (Desktop) (101022) Vacuum Package - 220V (101052) or 110V (101018) Dissection Stereo Microscope - Zeiss Stemi 305 (400484) Light Source CL4500 LED (400599) Dissection Tool kit (101017) Open Heating Bath Circulator – 220V (400740) or 110V (400737 |
NICE-TO-HAVE
Force Transducer – isometric (300172) Gas Supply Manifold (300295) Wire - 25µm (tungsten) (300096) Extended Warranty +3 years (101034) or Extended Warranty +8 years (101035) |
Murine breast cancer feed arteries are thin-walled with reduced α1A-adrenoceptor expression and attenuated sympathetic vasocontraction
Anne Sofie Froelunde, Marit Ohlenbusch, Kristoffer B. Hansen, Nicolai Jessen, Sukhan Kim and Ebbe Boetkjer
Breast Cancer Research2018, Published: 22 March 2018
Anne Sofie Froelunde, Marit Ohlenbusch, Kristoffer B. Hansen, Nicolai Jessen, Sukhan Kim and Ebbe Boetkjer
Breast Cancer Research2018, Published: 22 March 2018
Calcium oscillations in human mesenteric vascular smooth muscle
Navarro-Dorado, Garcia-Alonso, van Breemen, Tejerina, Fameli, Biochem Biophys Res Commun. 2014 Feb
TMEM16A knockdown abrogates two different Ca2+-activated Cl - currents and
contractility of smooth muscle in rat mesenteric small arteries
Dam VS, Boedtkjer DM, Nyvad J, Aalkjaer C, Matchkov V.
Navarro-Dorado, Garcia-Alonso, van Breemen, Tejerina, Fameli, Biochem Biophys Res Commun. 2014 Feb
TMEM16A knockdown abrogates two different Ca2+-activated Cl - currents and
contractility of smooth muscle in rat mesenteric small arteries
Dam VS, Boedtkjer DM, Nyvad J, Aalkjaer C, Matchkov V.
