Measuring What Holds Life Together
At the Center for Cardiovascular Genetics and Gene Diagnostics in Switzerland, Dr. Janine Meienberg and Valeria Turco investigate rare inherited connective-tissue disorders that can weaken the aorta and place patients at risk of severe vascular events.
Their work uses murine aortic samples to measure the maximum force the tissue can withstand before rupture. This provides a direct, quantitative way to compare healthy and diseased vessels, as well as treated and untreated samples.
Three DMT Tissue Puller systems support the team’s work with small, delicate aortic preparations, helping them obtain reproducible rupture-force measurements under controlled liquid conditions.
