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Myograph Service check
To make sure that your myograph works at optimal performance DMT offer our customers a myograph service check at a very favourable price.
Custom Myograph design
Apart from making our standard myograph systems, we offer our experience in developing and manufacturing equipment for use in the biomedical and pharmaceutical industry.
We offer up-to-date technologies including CNC milling, turning, CAD/CAM works etc. and can assist you with;
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Custom-made Myograph System
The 900MS 4-channel Myograph System is a custom-made system (developed in collaboration with the laboratory of Prof. Avril Somlyo) for molecular studies that focus on the contractile proteins and force development signal transduction research.
Key features of this custom-made system are very low volume baths for skinning or permeabilizing small muscle preparations and moving them easily between different cell internal solutions that mimic intracellular environments.
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Custom-made skinned small muscle ring myograph.
Developed in coorperation with Prof. Avril Somlyo,
University of Virginia VA, USA |
The system has 4 independent heated channels. Individual micro-stirring of the small volumes, heating and cooling capability for Q10 studies, and a very sensitive force transducer (μN sensitivity) that is robust to withstand handling.
Permeabilization in the 900MS will benefit pharmacological and physiological studies into the signal transduction cascade leading to force generation and studies of the calcium-sensitivity of force. Skinning will benefit physiological and biophysical studies in the molecular mechanisms of force development and actin-myosin interaction.
Please contact DMT directly for many of the advanced options available for the systems or new related products in the cardiac/skeletal muscle research field. |
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