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DMT Vessel Acquisition Suite (DMT VAS) is a new, improved software platform used in conjunction with DMT pressure myograph systems and is compatible with the 110P, 110PXL, 111P, 115FP, 120CP, 202CM, and 204CM lines of pressure and culture myographs.
The core function of the DMT VAS Software package is to acquire diameter measurements from pressurized vessels. Flow measurements using the DMT 161FM flow meter are now integrated into this single software package. Other pertinent vascular-related data can now be easily obtained in DMT VAS without having to manually calculate parameters such as vascular resistance, shear stress, or Reynolds number, an index that reflects turbulent or laminar flow.
The DMT VAS dimensioning software offers a more flexible, more powerful acquisition platform with more precise control and enhanced functionality. DMT VAS promises to simplify, as well as improve, data acquisition whether the experiments involve using pharmacology, investigating mechanisms related to myogenic responses, or unveiling vasculopathies involving defects in flow- or shear stress-mediated dilation.
Features of DMT Vessel Acquisition Suite
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Multiple imaging windows – allows the measurement of up to 4 different regions simultaneously.
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Line-averaging - unlike conventional “edge detection”, where contrast information is evaluated on a single line, DMT VAS averages contrast over all of the lines within a user-defined region to minimize the contribution of contrast that doesn’t occur over all lines. Images no longer need to be super-saturated or blurred to drown out the contrast from remnants of blood, fat, folding, etc., making diameter measurements easier and more accurate.
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Auto-gained contrast – a user-interface feature that allows precise control of image thresholds for more accurate and reliable edge detection.
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Real-time calculations and tracking of:
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- Inner and outer vascular diameters |
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- Left, right and average wall thickness
- Inner and outer cross-sectional areas
- Media to lumen ratios
- Flow
- Vascular resistance
- Shear stress
- Reynolds numbe |
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Improvements in DMT Vessel Acquisition Suite
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Multiple Imaging Windows – Having the flexibility of measuring up to 4 different regions of a mounted vessel means that interesting vascular anomalies and variability in a single preparation can be measured and observed.
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Line-Averaging – The new algorithm used for edge detection improves edge tracking, especially in vessels that are harder to completely "clean", decreasing the likelihood of having to "throw away data" because of poor imaging and tracking, thereby increasing productivity.
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Integrated Flow Measurements – Previous flow software was run simultaneously with dimension analysis, making data collection complicated and tedious, having to "flip" between 2 separate program windows to monitor experimental progress. DMT VAS has integrated the flow measurement tasks with the dimensioning tasks so that ALL collected pressure myography data are in a single file.
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Trace Recordings – data from previous dimensioning software had to either be recorded by hand or dumped into a tedious Excel sheet. The new Trace Recordings feature allows all measured and calculated parameters to be saved as trace data, simplifying data analysis in the end.
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Event Markers – the new Event Markers feature complements the new Trace Recordings feature by allowing the user to more precisely and accurately record events, changes or additions during the experiment, eliminating the need to mark time and events separately.
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